Research data is the original Intellectual Property produced by researcher that is then reported and interpreted in scholarly books, journal articles, and conference proceedings. This collection is a store of research data produced by Oxford Brookes researchers so that their data can be accessed by other researchers and the public.
Recent work putatively linked a rare genetic variant of the chaperone Resistant to Inhibitors of acetylcholinesterase (RIC3) (NM_024557.4:c.262G>A, NP_078833.3:p.G88R) to a unique ability to speak backwards, a language skill that is associated with exceptional working memory capacity. RIC3 is important for the folding, maturation, and functional expression of α7 nicotinic acetylcholine receptors (nAChR). We compared and contrasted the effects of RIC3G88R on assembly, cell surface expression, and function of human α7 receptors using fluorescent protein tagged α7 nAChR and Förster resonance energy transfer (FRET) microscopy imaging in combination with functional assays and 125I-α-bungarotoxin binding. As expected, the wild-type RIC3 protein was found to increase both cell surface and functional expression of α7 receptors. In contrast, the variant form of RIC3 decreased both. FRET analysis showed that RICG88R increased the interactions between RIC3 and α7 protein in the endoplasmic reticulum. These results provi…
Supplementary data for the PhD thesis 'The genetic mechanisms that coordinate the development and morphological divergence of Drosophila genital structures' by Amber Mae Ridgway
Financial Technology popularly referred to as “Fintech”, is said to be financial innovation facilitated by technology to change the way financial goods or services- like loans and investment are accessed by businesses and individuals. Fintech introduced a new dimension into the Financial System of Nigeria, however there is limited empirical studies into the relationship between Fintech and Financial development. Hence, this study employed variables that measures financial access, depth and stability of the system, using the World Bank Global Financial Development 4x2 framework as a guide. The study covers years 2002 – 2021; with 2002 to 2013 being the pre-Fintech prominence era in comparison to period 2014 to 2021 as the Fintech prominence era. Although data limitation meant that the empirical study could only look into years 2009 – 2019. Transaction values of Fintech channels were employed as the explanatory variables, to check their impact on some dependent variables that represents financial products and s…
This is a report detailing the process and findings of a mixed-methods study, funded by the General Nursing Council England and Wales Trust, aimed to identify changes in school nurse practice working with children and young people, to explore the benefits and challenges in school nurse work to support vulnerable children and young people during the pandemic, map new ways of working, and consider the use of these going forward.
Self-concordance theory and the goal-striving reasons framework both measure the quality of people’s reasons for their goal pursuits. Both have provided substantial evidence for their predictive power for people’s well-being. However, it remains unclear which of the two goal-reason models is the better predictor for different forms of well-being. The paper analyses the distinct relationships of the two models in relation to hedonic well-being (Subjective Well-Being, Life Satisfaction, Affect Balance) and indicators of eudaimonic well-being (Basic Need Satisfaction, Purpose and Self-Acceptance). The findings are based on a cross-sectional, correlative research design based (N = 124). Using multiple regression analyses the results show that the goal-striving reasons framework is overall more strongly associated with hedonic and eudaimonic well-being. However, the differences for hedonic well-being as well as for self-acceptance and purpose are much larger than they are for the three basic needs of autonomy, com…
During 2019-20 a qualitative study of the learning experiences of BAME students at a post 92 university was carried out. Utilising focus groups, the study aimed to explore experiences of teaching and learning. The data uploaded to RADAR are the transcripts from the focus groups.
The data extracted from 69 papers that made up our meta-analysis.
This glossary has been produced to support the documentation processes of the Endangered Wooden Architecture Programme. The Endangered Wooden Architecture Programme is a grant-giving programme that offers small and large grants for the documentation of endangered wooden architecture. The programme is hosted by Oxford Brookes University and delivered in collaboration with CyArk. EWAP was established in 2021 with funding from Arcadia, a charitable fund of Lisbet Rausing and Peter Baldwin.
There has been an increase in the number of UK university students disclosing mental health conditions in recent years. This dataset informed a paper that describes the evaluation of the Mind Tutor app, an artificial intelligence based wellbeing app specifically designed for first year undergraduate students, which included a chatbot function that guided students to relevant wellbeing content. The content of the app was developed based on data about mental health and wellbeing issues reported by students and focussed on anxiety, low mood, academic study, transition to university and relationships. Two randomised controlled evaluation studies were conducted with N = 177 and N = 240 first year undergraduate students from two UK universities (the second due to delays in development work and difficulties with recruitment in the first trial). The Mind Tutor had no significant impact on student wellbeing. The study suffered from poor recruitment and retention rates. However, further research is warranted to underst…
This paper will analyse the likeliness of being punished due to an accusation of male sexual deviance in Spain or England. In this vein, the paper includes primary sources involving doctors' role in these procedures. Regarding the legal treatment of sexual deviants, this paper will compare the data offered by the press respecting two case studies from each country. As a conclusion, British law proved to be more restrictive than the Spanish. Therefore, British male sexual deviants had fewer possibilities to avoid being judged and punished than the Spanish.