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The unprecedented success of Italian crime drama serial Gomorrah – The Series has spurred much interest in the industry as well as a lively critical debate. Little attention, however, has thus far been paid to the creative process behind the series. This article contributes to filling this gap by investigating the branding strategies and the writing strategies that have informed the development process. Particular emphasis is given to the analysis of the storylining techniques employed in the development of the arcs of Season 1 with a view to unpacking how, in turn, these determine mechanisms of the viewers’ engagement with characters. As typical of much contemporary serial dramas, these are predominantly antiheroes and therefore our allegiance to them is questioned when problematic issues are raised, as in the case of violent actions and dubious moral choices. The investigation combines three interplaying methodologies – i.e. a genetic approach, close textual (quantitative and qualitative) analysis and a co…
Rice straw is a major crop residue which is burnt in many countries, creating signicant air pollution. Thus, alternative routes for disposal of rice straw are needed. Biotechnological treatment of rice straw hydrolysate has potential to convert this agriculture waste into valuable biofuel(s) and platform chemicals. Geobacillus thermoglucosidasius is a thermophile with properties specially suited for use as a biocatalyst in lignocellulosic bioprocesses, such as high optimal temperature and tolerance to high levels of ethanol. However, the capabilities of Geobacillus thermoglucosidasius to utilize sugars in rice straw hydrolysate for making bioethanol and other platform chemicals have not been fully explored. In this work, we have created a genome scale metabolic model (denoted iGT736) of the organism containing 736 gene products, 1159 reactions and 1163 metabolites. The model was validated both by purely theoretical approaches and by comparing the behaviour of the model to previously published experimental res…
Background: The baobab fruit is high in both dietary fibre and polyphenols and therefore may increase satiety. The aim of the study was to measure the effects of baobab fruit extract on satiety.
Methods: The study was conducted on 20 healthy participants. The study was a one day single blind crossover design. Participants were randomised to either a test smoothie consisting of 15g of baobab extract or a control smoothie without the addition of baobab. Subjective ratings of satiety were taken on visual analogue scales immediately pre consumption and then post consumption, and energy intake at a post ad libitum meal was recorded.
Results: Subjective measures of hunger were reduced following the test smoothie compared to the control (p<0.05). There was no significant difference in calorie intake at an ad libitum meal.
Conclusions: This research has positive implications for the use of baobab for reducing hunger, possibly having a positive effect on weight maintenance.
Large general population surveys show that heavy regular and episodic alcohol consumption are associated with lower intakes of fruits and vegetables, and higher intakes of processed and fried meat. This is of particular concern regarding pregnant women, as both alcohol intake and inadequate maternal nutrition are independently associated with adverse fetal outcomes. The current study aimed to determine associations between maternal dietary patterns and alcohol consumption during pregnancy.
Secondary analysis of data from the Avon Longitudinal Study of Parents and Children (ALSPAC). Women provided details of alcohol consumption at 18 weeks’ gestation and diet at 32 weeks’ gestation (n=9,839. Dietary patterns were derived from the food frequency questionnaire data using principal components analysis. Associations between alcohol consumption and dietary patterns were determined using multiple linear regression, adjusted for various socio-demographic and lifestyle factors.
A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language disorders are highly heritable with substantial societal impact. Molecular studies have begun to identify candidate loci, but much of the underlying genetic architecture remains undetermined. We performed whole-exome sequencing of 43 unrelated probands affected by severe specific language impairment, followed by independent validations with Sanger sequencing, and analyses of segregation patterns in parents and siblings, to shed new light on aetiology. By first focusing on a pre-defined set of known candidates from the literature, we identified potentially pathogenic variants in genes already implicated in diverse language-related syndromes, including ERC1, GRIN2A, and SRPX2. Complementary analyses suggested novel putative candidates carrying validated variants which were predicted to have functional effects, such as OXR1, SCN9A and KMT2D. W…
Studies across many languages (e.g., Dutch, English, Farsi, Spanish, Xhosa) have failed to show early acquisition of subject-verb agreement, while recent studies on French reveal acquisition by 30 months of age. Using a similar procedure as in previous French studies, the present study evaluated whether earlier comprehension of subject-verb agreement in (Mexican) Spanish can be revealed when task demands are lowered. Two experiments using a touch-screen pointing task tested comprehension of SV agreement by monolingual Spanish-speaking children growing up in Mexico City, between about 3 and 5 years of age. In Experiment 1, the auditory stimuli consisted of a transitive verb+pseudonoun object (e.g. agarra el micho ‘he throws the micho’ vs. agarran el duco ‘they throw the duco’); results failed to show early comprehension of SV agreement, replicating previous findings. In Experiment 2, the same stimuli were used, with the crucial difference that the word objeto ‘object’ replaced all pseudonouns; results reveale…
Prostate cancer (PCa) can negatively impact on men’s sexual, urinary and emotional functioning, affecting quality of life. Most men with PCa are older (>= 65 years), married and heterosexual and little is known about the impact on men who are younger, unpartnered or gay. We aimed to synthesise existing qualitative research on these three groups of men. A systematic metasynthesis was undertaken that included data on the unique impacts of PCa on younger (<65 years) (n=7 papers), unpartnered (n=17 papers), or gay or bisexual men (n=11 papers) using a modified meta-ethnographic approach. The three overarching constructs illustrated the magnified disruption to men’s biographies, that included: marginalisation, isolation and stigma– relating to men’s sense of being ‘out of sync’; the burden of emotional and embodied vulnerabilities and the assault on identity– illustrating the multiple threats to men’s work, sexual and social identities; shifting into different communities of practice– such as the shift from being …
UK and wider EU governments follow gender neutral policies in their disaster planning and management based upon a misconception that the gender gap has been eliminated. Findings from our quantitative and qualitative research, carried out as a part of an EU Project, ‘MICRODIS’, in two flood affected locations in England (Tewkesbury floods of 2007, and Morpeth floods of 2008), challenges this notion, revealing that disasters can have paradoxically equal and yet differentiated gendered impacts. Our findings highlight some of the more subtle ways that disasters differentially impacted women and men. It shows that although the degree of mental health recovery of affected men and women was mostly equal, they mobilised different recovery strategies, mostly consistent with their traditional gendered norms and socially constructed roles. Women's recovery strategies were mainly aligned with emotional notions of care, while men's were with notions of control. These findings also show that gendered identities, home-neigh…
There has in recent years, been much media speculation and consumer interest in the beneficial satiating properties of consuming coconut oil and it’s potential to aid weight loss. However the media has primarily cited studies using MCT oil. The current perspective looks at the research that is available on coconut oil. It examines if and how MCT related research can be applied to coconut oil and if there is potential for coconut oil to aid weight loss. The current report indicates a lack of consistent evidence on the topic of coconut oil, satiety and weight loss. Given both the publicity and the increased consumption of coconut oil further research, particularly long term clinical trials, in this area are warranted.