Journal Article

Language and reading impairments are associated with increased prevalence of non-right handedness

Abstract

Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6–19 years old; European ethnicity) using a priori set criteria. A meta-analysis (Ncases = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06–1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions.

Attached files

Authors

Abbondanza, Filippo
Dale, Philip S.
Wang, Carol A.
Hayiou-Thomas, Marianna E.
Toseeb, Umar
Koomar, Tanner S.
Wigg, Karen G.
Feng Yu
Price, Kaitlyn M.
Kerr, Elizabeth N.
Guger, Sharon L.
Lovett, Maureen W.
Strug, Lisa J.
van Bergen, Elsje
Dolan, Conor V.
Tomblin, J. Bruce
Moll, Kristina
Schulte-Körne, Gerd
Neuhoff, Nina
Warnke, Andreas
Fisher, Simon E.
Barr, Cathy L.
Michaelson, Jacob J.
Boomsma, Dorret I.
Snowling, Margaret J.
Hulme, Charles
Whitehouse, Andrew J.O.
Pennell, Craig E.
Newbury, Dianne F.
Stein, John
Talcott, Joel B.
Bishop, Dorothy V.M.
Paracchini, Silvia

Oxford Brookes departments

Department of Biological and Medical Sciences

Dates

Year of publication: 2023
Date of RADAR deposit: 2022-12-13

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This work is licensed under a Creative Commons Attribution 4.0 International License

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