Journal Article


Adjuvant endocrine therapy after breast cancer: A qualitative study of factors associated with adherence

Abstract

Introduction : Despite evidence of the efficacy of Adjuvant Endocrine Therapy (AET) in reducing the risk of recurrence and mortality after treatment for primary breast cancer, adherence to AET is suboptimal. This study aimed to explore factors that influence adherence and non-adherence to adjuvant endocrine therapy (AET) following breast cancer to inform the development of supportive interventions. Methods: Interviews were conducted with 32 women who had been prescribed AET, 2-4 years following their diagnosis of breast cancer,. Both adherers (n=19) and non-adherers (n=13) were recruited. The analysis was conducted using the Framework approach. Results: Factors associated with adherence were: Managing side effects including information and advice on side effects, and taking control of side effects, Supportive relationships, and Personal influences. Factors associated with non-adherence were: Burden of side effects, Feeling unsupported, Concerns about long term AET use, Re-gaining normality, including valuing quality of life over length of life, and Risk perception Conclusions: Provision of timely information to prepare women for the potential side effects of AET and education on medication management strategies are needed, including provision of timely and accurate information on the efficacy of AET in reducing breast cancer recurrence, and on potential side effects and ways to manage these should they arise. . Trust in the doctor-patient relationship and clear patient pathways for bothersome side effects and concerns with AET are important. Training and education around AET for GPs should be considered alongside novel care pathways such as primary care nurse cancer care review, and community pharmacist follow-up.

Attached files

Authors

Brett, Jo
Boulton, Mary
Fenlon, Debbie
Hulbert-Williams, Nick J.
Walter, Fiona M.
Donnelly, Peter
Lavery, Bernadette
Morgan, Adrienne
Morris, Carolyn
Watson, Eila

Oxford Brookes departments

Faculty of Health and Life Sciences

Dates

Year of publication: 2018
Date of RADAR deposit: 2017-11-01


Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License


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This RADAR resource is the Version of Record of Adjuvant endocrine therapy after breast cancer: A qualitative study of factors associated with adherence

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  • Owner: Joseph Ripp
  • Collection: Outputs
  • Version: 1 (show all)
  • Status: Live