This community resource paper introduces the range of materials developed by the INDEPTH (Impact of Nuclear Domains on Gene Expression and Plant Traits) COST Action made available through the INDEPTH Academy. Recent rapid growth in understanding of the significance of epigenetic controls in plant and crop science has led to a need for shared, high-quality resources, standardisation of protocols and repositories for open access data. The INDEPTH Academy provides a range of masterclass tutorials, standardised protocols and teaching webinars together with a rapidly developing repository to support imaging and spatial analysis of the nucleus and deep-learning for automated analysis. These resources were developed partly as a response to the COVID-19 pandemic, but also driven by needs and opportunities identified by the INDEPTH community of around 200 researchers in 80 laboratories from 32 countries. This community report outlines the resources produced and how they will be extended beyond the INDEPTH project, but also aims to encourage the wider community to engage with epigenetics and nuclear structure by accessing these resources.
Tatout, ChristopheMougeot, Guillaume
Parry, GeraintBaroux, CéliaPradillo, MónicaEvans, David
Department of Biological and Medical Sciences
Year of publication: 2022Date of RADAR deposit: 2022-02-03