Journal Article

Thalamic deep brain stimulation may relieve breathlessness in COPD


The cerebral mechanisms of dyspnoea (breathlessness) are not well understood. Neuroimaging studies of experimentally induced dyspnoea in healthy individuals have identified several cortical areas that might form a neural network for perception of dyspnoea [1], much like those identified for pain perception [2]. However, functional imaging studies alone do not reveal neurophysiological pathways and may miss putative targets for dyspnoea relief. The objective of this study was to assess the effects of Deep Brain Stimulation (DBS) of four different brain nuclei on the sensation of dyspnoea in an individual with Chronic Obstructive Pulmonary Disease (COPD) using an established multidimensional dyspnoea tool [3].

Attached files


Green, AL
Debrah, E
Roy, H
Rebelo, P
Moosavi, SH

Oxford Brookes departments

Faculty of Health and Life Sciences\Department of Biological and Medical Sciences


Year of publication: 2019
Date of RADAR deposit: 2019-03-20

Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

Related resources

This RADAR resource is the Accepted Manuscript of Thalamic deep brain stimulation may relieve breathlessness in COPD


  • Owner: Daniel Croft
  • Collection: Outputs
  • Version: 1 (show all)
  • Status: Live
  • Views (since Sept 2022): 176