Clostridium autoethanogenum is an industrial microbe used for the commercial-scale production of ethanol from carbon monoxide. While significant progress has been made in the attempted diversification of this bioprocess, further improvements are desirable, particularly in the formation of the high-value platform chemicals, such as 2,3-butanediol. A new, experimentally parameterised genome scale model of C. autoethanogenum predicts dramatically increased 2,3-butanediol production under non-carbon-limited conditions when thermodynamic constraints on hydrogen production are considered.
Norman, RupertMillat, ThomasSchatschneider, SarahHenstra, AnneBreitkopf, RonjaPander, BartAnnan, FlorencePiatek, PawelHartman, HassanPoolman, MarkFell, DavidWinzer, KlausMinton, NigelHodgman, Charlie
Faculty of Health and Life Sciences\Department of Biological and Medical Sciences
Year of publication: 2019Date of RADAR deposit: 2019-04-18