Journal Article

A new synthesis and preliminary evaluation of some analogues of mecamylamine – a compound with anti-addiction properties

Abstract

A new synthesis of mecamylamine – a known anti-hypertensive drug with anti-addictive properties is described. The new route allowed access to two novel analogues whose activity at two nicotinic acetylcholine receptor subtypes was assessed.

Attached files

Authors

Mangan, David
McNabola, Nessa
Clark, Emily H.
Bermudez-Diaz, Isabel
Wonnacott, Susan
Southern, J. Mike

Oxford Brookes departments

Faculty of Health and Life Sciences\Department of Biological and Medical Sciences

Dates

Year of publication: 2016
Date of RADAR deposit: 2017-01-10

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

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Related resources

This RADAR resource is the Accepted Manuscript of A new synthesis and preliminary evaluation of some analogues of mecamylamine – a compound with anti-addiction properties