Millet is a grain high in polyphenols and antioxidants, which are bioactive compounds known
to influence blood glucose response. The aim of this study was to compare the effect of finger
millet muffin and wheat muffin on glycaemic response (GR), insulin response (IR), gastric
emptying (GE) and satiety in healthy individuals and people with prediabetes. In a single
blind randomised controlled crossover trial at Oxford Brookes Centre for Nutrition and
Health, 15 healthy individuals and 14 individuals with prediabetes were recruited between
May and December 2017. The participants’ GR (3 hours), IR (3 hours), GE (4 hours) and
satiety (4 hours) were measured before and after the consumption of muffins. A mixed
method analysis of variance was used to compare GE and the incremental area under the
curve (iAUC) for GR and IR between the participant groups and muffins. There was a
significant interaction between participants and muffins on IR iAUC at 180 min (p = 0.042).
A significant effect of muffins was found on the GR peak (p = 0.013). The millet muffin
decreased the GR peak and IR iAUC compared with the wheat muffin in participants with
prediabetes. A significant interaction between participants and muffins for GE ascension time
Tasc (p = 0.017) was observed; with no effect of muffins on satiety AUC in the participant
groups. This study suggested that polyphenol and fibre-rich finger millet may have the
potential to influence the management of prediabetes.
Almaski, AmeerahCoe, Shelly
Lightowler, HelenClegg, Miriam E.Thondre, Pariyarath S.
Department of Sport, Health Sciences and Social Work
Year of publication: 2022Date of RADAR deposit: 2022-05-23