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This Open Access version of the publication is the Version of Record.
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Background. We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation. Methods. Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%). Results. Regarding practices around brain death, we found agreement on the clinical evaluation (prerequisites and neurological assessment) for brain death determination (BDD) in 100% of the centers. However, ancillary tests were required for BDD in 64% of the centers. BDD for nondonor patients was deemed mandatory in 18% of the centers before withdrawing life-sustaining measures (LSM). Also, practices around postmortem organ donation varied. Organ donation after circulatory arrest was forbidden in 45% of the centers. When withdrawal of LSM was contemplated, in 67% of centers the patients with a ventricular drain in situ had this removed, either sometimes or all of the time. Conclusions. This study showed both agreement and some regional differences regarding practices around brain death and postmortem organ donation. We hope our results help quantify and understand potential differences, and provide impetus for current dialogs toward further harmonization of practices around brain death and postmortem organ donation.
Ernest van Veen
Mathieu van der Jagt
Maryse C. Cnossen
Andrew I.R. Maas
Inez D. de Beaufort
David K. Menon
Wim J.R. Rietdijk
Jeroen T.J.M. van Dijck
Erwin J.O. Kompanje
Faculty of Health and Life Sciences
brain death, ethics, postmortem organ donation, traumatic brain injury, ventricular drainage, withdrawing life-sustaining measures
van Veen, E., van der Jagt, M., Cnossen, M., Maas, A., de Beaufort, I., Menon, D., Citerio, G., Stocchetti, N., Rietdijk, W., van Dijck, J., Kompanje, E., Dawes, H., Collett, J. and Esser, P.
(2018) 'Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study', Critical Care, 22(306).
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