In order to start to explore the possibilities for makerspaces as a new learning space within Academic Library services in Higher Education (HE), this original research study ask two key questions: 1) How is learning achieved and supported in makerspaces? 2) What can Academic Library services bring to the effective organisation and support of makerspaces?
Design/ Methodology/ Approach An extensive literature review is followed by a Template Analysis (King, 2012) of data from an online forum of three professionals operating makerspaces in Academic Library services in the US, and a discussion incorporating relevant educational theory and philosophy.
Findings The three overarching learning themes found were: Experiential Learning (Dewey, 1909; Kolb, 1984), Communities of Practice (Lave and Wenger, 1991) and Self-efficacy through social learning (Bandura, 1997).
Research limitations/ implications The one week forum of three professional library staff provided detailed and informative data. Substan…
Species composition of Necator hookworms was surveyed in (i) Ugandan chimpanzees living around farms and villages at Bulindi, (ii) Gabonese gorillas under habituation in Moukalaba-Doudou National Park (MDNP), and (iii) Gabonese villagers living adjacent to MDNP. Internal transcribed spacers (ITS) of rDNA and partial cytochrome c oxidase subunit 1 (Cox1) gene of mtDNA were analyzed from larvae obtained by coproculture. Three ITS types (I, II and III) and three Cox1 haplotype groups (A, B and C) were demonstrated. ITS type I and Cox1 haplotype group A, representing Necator americanus, were demonstrated in the hookworm larvae from Gabonese gorillas and humans, but not from Ugandan chimpanzees. Type II and haplotype groups B and C, presumably representing N. gorillae, were found in larvae from Ugandan chimpanzees and Gabonese gorillas and humans. These features were overall similar with those found previously in the Central African Republic. Meanwhile, type III was proven in a larva from a Gabonese gorilla as the…
George Orwell's relections on his own preparatory school education, and his subsequent work as an unqualiied private school teacher, highlight many of the weaknesses associated with
a factual and rote based teaching and learning of history. These insights are timely given the return to a knowledge-based curriculum in the recent National Curriculum reforms. The long- standing debate between progressive and traditionalist approaches to history is outlined and a case made that ultimately historical understanding requires both knowledge and skills. Orwell also identiied the importance of visual imagery as a starting point for historical reasoning, something that has rarely received recognition from history educators.
Contemporary Conservative education policy may seem to be hastily formulated and executed, but it is arguedly founded on deeply held ideological beliefs. By briefly examining the history of the British Conservative party, including its complex formation and disparate ideological traditions, including the broader conservative diaspora, four key elements of Conservative educational beliefs, namely support for traditional practices, anti-intellectualism, economic liberalism and the power of the market, and support for inequalities of outcome, are discussed. These beliefs are then examined against contemporary policy initiatives such as practice based teacher training, the marketisation of schools and curriculum reform.
Metastasis accounts for most of the deaths from breast cancer and the preference of invasive breast cancer metastasising to bone has been widely reported. However, the biological basis of breast cancer osteotropism is not fully understood. This paper provides, for the first time, an integrative, systematic review of evidence of molecular factors that have functional roles in the homing of metastatic breast cancer to the bone.
Pubmed, Web of Science and EBSCOhost were searched using keywords and synonyms for molecular, metastasis, breast cancer and bone to identify articles published between January 2004 and August 2016. 4,491 potentially relevant citations were retrieved. 63 articles met the inclusion criteria, which were primary studies reporting evidence of molecular factors that have functional roles in predisposing breast cancer bone metastasis in vivo.12 of those 63 articles that additionally met quality criteria were included in the review. Extracted data were tabulated and key findings that indicated …
Background: Encouraging institutional birth is an important component of reducing maternal mortality in low-resource settings. This study aims to identify and understand the determinants of persistently low institutional birth in rural Nepal, with the goal of informing future interventions to reduce high rates of maternal mortality.
Methods: Postpartum women giving birth in the catchment area population of a district-level hospital in the Far-Western Development Region of Nepal were invited to complete a cross-sectional survey in 2012 about their recent birth experience. Quantitative and qualitative methods were
used to determine the institutional birth rate, social and demographic predictors of institutional birth, and barriers to institutional birth.
Results: The institutional birth rate for the hospital's catchment area population was calculated to be 0.30 (54 home births, 23 facility births). Institutional birth was more likely as age decreased (ORs in the range of 0.20-0.28) and as income increased (O…
Background: Impaired sleep is associated with negative effects on quality of life and daytime functioning. Higher rates of sleep disturbance are reported in children with various developmental disorders. However, little is known about sleep in children with developmental
coordination disorder (DCD), a condition characterized by everyday movement difficulties. Previously, in a preliminary study, we found higher rates of parent-reported sleep disturbance in children with DCD compared to controls.
Aims: To examine sleep in DCD using objective measures and to examine links with daytime fatigue and sleepiness.
Methods: Two groups (primary and secondary school-aged) of 15 children with DCD, plus matched controls, participated. Parent-reported child sleep was assessed using the Children’s Sleep Habits Questionnaire and actigraphy provided an objective measure of sleep–wake patterns over 1 week (including weekdays and weekend). Pediatric restless legs syndrome (RLS) semi-structured diagnostic interview was conducte…
The LInker of Nucleoskeleton and Cytoskeleton (LINC) complex is an evolutionary well-conserved protein bridge connecting the cytoplasmic and nuclear compartments across the nuclear membrane. While recent data support its function in nuclear morphology and meiosis, its implication in chromatin organisation has not been studied in plants. Here 3D imaging methods have been used to investigate nuclear morphology and chromatin organisation in interphase nuclei of the model plant Arabidopsis thaliana, in which heterochromatin cluster in conspicuous chromatin domains called chromocentres. Chromocentres form a repressive chromatin environment contributing to transcriptional silencing of repeated sequences, a general mechanism needed for genome stability. Quantitative measurements of 3D position of chromocentres indicate their close proximity to the nuclear periphery but that their position varies with nuclear volume and can be altered in specific mutants affecting the LINC complex. Finally we propose that the plant …
In this study, we explore the plasticity during evolution of proteins of the higher plant nuclear envelope (NE) from the most ancestral plant species to advanced angiosperms. The higher
plant NE contains a functional Linker of Nucleoskeleton and Cytoskeleton (LINC) complex based on conserved Sad1-Unc84 (SUN) domain proteins and plant specific Klarsicht/Anc1/Syne homology (KASH) domain proteins. Recent evidence suggests the presence of a plant lamina underneath the inner membrane and various coiled-coil proteins have been hypothesised to be associated with it including Crowded Nuclei (CRWN; also termed LINC and NMCP), Nuclear Envelope Associated Protein (NEAP) protein families as well as the CRWN binding protein KAKU4. SUN domain proteins appear throughout with a key role for mid-SUN proteins suggested. Evolution of KASH domain proteins has resulted in increasing complexity, with some appearing in all species considered, while other KASH proteins are progressively gained during evolution. Failure to identify C…
To assess the feasibility of Zumba Gold® in people with PD, and to investigate the effects of dance styles and number of sessions on activity levels and physiological load.
Repeated measure uncontrolled (single group) feasibility study.
Eleven participants (age: 64.0 ± 8.1 years) with mild-to-moderate idiopathic PD (Hoehn & Yahr stage < 3.0) took part in a screening session, followed by six Zumba Gold® workouts each separated by one week, and a follow-up interview six months later.
Main outcome measures
The main feasibility parameters measured were retention, compliance, and adverse events. Furthermore, during each Zumba Gold® session, physical activity levels were measured using tri-axial accelerometers, while physiological load was assessed by average heart rate (HRmean). A two-way ANOVA with repeated measures assessed the effects of dance styles and session number on activity level and HR.
73% retention and 81% compliance were achieved, and no adverse events were recor…